# Typhoid

> The content on this page is for informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. If you have health concerns, consult a qualified healthcare professional. Medova is not a medical service provider.

Source: https://medova.health/en/knowledge/vaccines/typhoid · Language: en

## Vaccine Information

- Type: Subunit
- Administration: Injection
- WHO Code: TYVi
- Travel Recommended: Yes

**Pregnancy: Safe if travel warrants vaccination.**

Injectable typhoid ViCPS (Vi polysaccharide) vaccine is an inactivated subunit vaccine and is considered safe during pregnancy when the risk of typhoid fever warrants vaccination.


- Limited formal studies in pregnancy, but extensive post-marketing experience with no safety signals.

- Preferred over oral Ty21a (live vaccine) during pregnancy.

- WHO recommends vaccination for pregnant travelers to highly endemic areas (South Asia in particular).

**Breastfeeding: Safe — no restrictions.**

Injectable typhoid ViCPS vaccine is inactivated and poses no risk during breastfeeding. No modification to breastfeeding or vaccination schedule is required.

**Pediatric use:**


- Injectable ViCPS: licensed from **2 years** of age.

- Children <2 years: ViCPS is not effective due to T-cell-independent polysaccharide response immaturity.

- Typhoid conjugate vaccine (TCV, e.g., Typbar-TCV): licensed from 6 months — preferred for young children in endemic settings (WHO prequalified).

- Single 0.5 mL IM dose. Revaccinate every 2–3 years if continued exposure.

**Geriatric use:**


- No specific age-related concerns. Standard dose and schedule apply.

- Immune response may be slightly reduced in elderly adults, but clinically protective levels are typically achieved.

- Food and water precautions remain essential regardless of vaccination status.

## Side Effects

- Anaphylaxis (Very rare) — Serious
- Arthralgia (Uncommon)
- Chills (Uncommon)
- Dizziness (Uncommon)
- Fatigue (Common)
- Fever (Common)
- Generalized rash (Rare)
- Headache (Very common)
- Injection site induration (Common)
- Injection site pain (Very common)
- Injection site redness (Common)
- Injection site swelling (Common)
- Injection site warmth (Common)
- Limb pain (Common)
- Loss of appetite (Common)
- Malaise (Common)
- Myalgia (Common)
- Nausea (Common)
- Paresthesia (Very rare)
- Pruritus (Rare)
- Syncope (Rare)
- Urticaria (Rare)
- Vomiting (Uncommon)

## Contraindications

- Acute febrile illness (Precaution)
- Age below minimum recommended (Absolute)
- Anaphylaxis after previous dose (Absolute)
- Allergy to vaccine component (Absolute)
- Bleeding disorder (Precaution)

## Vaccination Schedule

No schedule data available.

## FAQ

**What are the side effects of Typhoid?**

Common side effects include: Anaphylaxis, Arthralgia, Chills, Dizziness, Fatigue.

**Who should not get Typhoid?**

Contraindications include: Acute febrile illness, Age below minimum recommended, Anaphylaxis after previous dose, Allergy to vaccine component, Bleeding disorder.

## Prevents

- [Typhoid Fever](https://medova.health/en/knowledge/diseases/typhoid-fever)

## Indications

- [Thailand](https://medova.health/en/knowledge/countries/thailand): Required
- [Myanmar](https://medova.health/en/knowledge/countries/myanmar): Recommended
- [Madagascar](https://medova.health/en/knowledge/countries/madagascar): Recommended
- [Indonesia](https://medova.health/en/knowledge/countries/indonesia): Recommended
- [Vietnam](https://medova.health/en/knowledge/countries/vietnam): Recommended
- [Guatemala](https://medova.health/en/knowledge/countries/guatemala): Recommended
- [Syrian Arab Republic](https://medova.health/en/knowledge/countries/syrian-arab-republic): Recommended
- [India](https://medova.health/en/knowledge/countries/india): Recommended
- [Bangladesh](https://medova.health/en/knowledge/countries/bangladesh): Recommended
- [Nepal](https://medova.health/en/knowledge/countries/nepal): Recommended

## Sources & content verification

- Data sources: WHO Position Papers 2024 + CDC Pink Book 2024 + EMA SmPC
- [www.who.int](https://www.who.int/teams/immunization-vaccines-and-biologicals/policies/position-papers)

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The content on this page is for informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. If you have health concerns, consult a qualified healthcare professional. Medova is not a medical service provider.

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